Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 18/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192730 | 0.94 | NOS2 (0.50) | NOS2FAAHPDE4A | |
| SCHEMBL5191064 | 0.89 | NOS2 (0.52) | NOS2 | |
| SCHEMBL5194980 | 0.89 | NOS2 (0.63) | NOS2 | |
| SCHEMBL5192012 | 0.89 | NOS2 (0.48) | NOS2 | |
| SCHEMBL5192797 | 0.88 | NOS2 (0.46) | NOS2 | |
| SCHEMBL5192168 | 0.88 | NOS2 (0.58) | NOS2FAAH | |
| SCHEMBL5192735 | 0.87 | NOS2 (0.54) | NOS2FAAH | |
| SCHEMBL5191748 | 0.86 | NOS2 (0.46) | NOS2 | |
| SCHEMBL5192862 | 0.85 | NOS2 (0.53) | NOS2 | |
| SCHEMBL5192601 | 0.85 | NOS2 (0.47) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| EP-0968206-B1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LAB (US) | 2006-11-15 | — | — | EP | disclosed |