Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490754 | 0.92 | MAPT (0.54) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7490755 | 0.92 | MAPT (0.54) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7487469 | 0.89 | MAPT (0.51) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7487475 | 0.89 | MAPT (0.51) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7487444 | 0.87 | GFER (0.69) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7487450 | 0.87 | GFER (0.69) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7482156 | 0.86 | MAPT (0.49) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7482142 | 0.86 | MAPT (0.49) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL15440479 | 0.86 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL922004 | 0.83 | GFER (0.49) | MAPTRAB9ASMN1; SMN2MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497368-B2 | Arylazo-heteroaryl compounds and their use for long-term thermal energy storage | BRANDEIS UNIVERSITY (US) | 2025-12-16 | — | — | US | disclosed |
| CN-116368224-A | ACE2 muteins and methods of use thereof | 壹鸣生物公司 | 2023-06-30 | — | — | CN | disclosed |
| EP-4168541-A2 | ACE2 MUTEINS AND METHODS OF USING THE SAME | Emmune, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |
| US-20230053197-A1 | ARYLAZO-HETEROARYL COMPOUNDS AND THEIR USE FOR LONG-TERM THERMAL ENERGY STORAGE | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2023-02-16 | — | — | US | disclosed |
| WO-2021158638-A1 | ARYLAZO-HETEROARYL COMPOUNDS AND THEIR USE FOR LONG-TERM THERMAL ENERGY STORAGE | BRANDEIS UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021122175-A1 | REVERSIBLE, OPTICALLY SWITCHABLE ADHESIVES BASED ON ARYLAZO-3,5-DIMETHYLISOXAZOLE DERIVATIVES | Westfälische Wilhelms-Universität Münster (DE) | 2021-06-24 | — | — | WO | disclosed |
| US-20170114044-A1 | PYRIDAZINONE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS AND METHODS OF TREATING DISORDERS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170114044-A1 | PYRIDAZINONE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS AND METHODS OF TREATING DISORDERS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170114044-A1 | PYRIDAZINONE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS AND METHODS OF TREATING DISORDERS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-04-27 | — | — | US | disclosed |
| US-9550756-B2 | Pyridazinone compounds as phosphodiesterase inhibitors and methods of treating disorders | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20100197651-A1 | Pyridazinone compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100197651-A1 | Pyridazinone compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20050272709-A1 | Immugenic compositions and diagnostic and therapeutic uses thereof | DERMIRA (CANADA), INC. | 2005-12-08 | — | — | US | disclosed |
| EP-1450791-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | Kinetek Pharmaceuticals, Inc. (CA) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045379-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-06-05 | — | — | WO | disclosed |
| US-6169087-B1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2001-01-02 | — | — | US | disclosed |
| EP-1017697-A1 | MODULES OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015529-A1 | MODULES OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 1999-04-01 | — | — | WO | disclosed |
| US-4006132-A | 1'-Formyl-1'-halobenzeneazomethane compounds having herbicidal activity | THE UPJOHN COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3932662-A | ANTHELMINTICS, PYRUVOYL CHLORIDE PHENYLHYDRAZONES | THE UPJOHN COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230053197-A1 | ARYLAZO-HETEROARYL COMPOUNDS AND THEIR USE FOR LONG-TERM THERMAL ENERGY STORAGE | NQO1, CBR1, AHR | MAPT 4221/4885RAB9A 883/4885SMN1; SMN2 1645/4885 |
| US-12497368-B2 | Arylazo-heteroaryl compounds and their use for long-term thermal energy storage | NQO1, RECQL, AHR | MAPT 2275/4885RAB9A 619/4885SMN1; SMN2 1735/4885 |
| US-20050272709-A1 | Immugenic compositions and diagnostic and therapeutic uses thereof | MKI67, CDK4, CCNC | MAPT 4000/4885RAB9A 3555/4885SMN1; SMN2 2243/4885 |
| US-20170114044-A1 | PYRIDAZINONE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS AND METHODS OF TREATING DISORDERS | PDE3A, PDE5A, PDE3B | MAPT 4321/4885RAB9A 904/4885SMN1; SMN2 3025/4885 |
| US-20100197651-A1 | Pyridazinone compounds | PDE3A, PDE5A, PDE3B | MAPT 4144/4885RAB9A 495/4885SMN1; SMN2 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.