SCHEMBL7487444

SCHEMBL7487444

CC(=O)/C(=N/Nc1ccccc1)C(=O)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.69
MAPT P10636 6/20 0.59
GAA P10253 3/20 0.59
KMT2A Q03164 3/20 0.59
MEN1 O00255 1/20 0.59
RECQL P46063 1/20 0.59
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
MAPK1 P28482 3/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.54
NAPRT Q6XQN6 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA7 P43166 1/20 0.47
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7487450 1.00 GFER (0.69) GFERMAPTGAAKMT2AMEN1
SCHEMBL2603162 0.92 GFER (0.61) GFERMAPTGAAKMT2AMEN1
SCHEMBL15216618 0.92 GFER (0.61) GFERMAPTGAAKMT2AMEN1
SCHEMBL519257 0.87 MAPT (0.56) GFERMAPTGAAKMT2AMEN1
SCHEMBL12998581 0.87 GFER (0.55) GFERMAPTGAAKMT2AMEN1
SCHEMBL12299581 0.85 GFER (0.52) GFERMAPTGAAKMT2AMEN1
SCHEMBL7490754 0.84 MAPT (0.54) GFERMAPTGAAKMT2AMEN1
SCHEMBL7490755 0.84 MAPT (0.54) GFERMAPTGAAKMT2AMEN1
SCHEMBL24384619 0.84 MAPT (0.53) GFERMAPTGAAKMT2AMEN1
SCHEMBL13707250 0.84 MAPT (0.53) GFERMAPTGAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004539-A1 MAGENTA TONER CONTAINING COMPOUND HAVING AZO SKELETON CANON KABUSHIKI KAISHA (JP) 2015-01-01 US disclosed
US-20140377697-A1 CYAN TONER CONTAINING COMPOUND HAVING AZO SKELETON CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
US-20140356779-A1 BLACK TONER CONTAINING COMPOUND HAVING AZO SKELETON CANON KABUAHIK KAISHA (JP) 2014-12-04 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
EP-0712402-B1 HYDROISOQUINOLINE DERIVATIVES SMITHKLINE BEECHAM SPA (IT) 2002-04-10 EP disclosed
US-5731322-A ADMINISTERING AS ANALGESICS OR IMMUNOMODULATING AND/OR CARDIOVASCULAR AGENTS SMITHKLINE BEECHAM S.P.A. (IT) 1998-03-24 US disclosed