Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195504 | 1.00 | PYGL (0.72) | PYGLCYP2C9 | |
| SCHEMBL5194489 | 0.99 | PYGL (0.70) | PYGLCYP2C9 | |
| SCHEMBL5194707 | 0.99 | PYGL (0.70) | PYGLCYP2C9 | |
| SCHEMBL5195135 | 0.93 | PYGL (0.72) | PYGLCYP2C9 | |
| SCHEMBL5192316 | 0.93 | PYGL (0.72) | PYGLCYP2C9 | |
| SCHEMBL5197748 | 0.93 | PYGL (0.61) | PYGLCYP2C9 | |
| SCHEMBL5195364 | 0.91 | PYGL (0.77) | PYGLCYP2C9 | |
| SCHEMBL5245756 | 0.91 | PYGL (0.77) | PYGLCYP2C9 | |
| SCHEMBL5194734 | 0.91 | PYGL (0.69) | PYGLCYP2C9 | |
| SCHEMBL5191950 | 0.91 | PYGL (0.69) | PYGLCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812383-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | Smithkline Beecham Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006052722-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-18 | — | — | WO | disclosed |