Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 9/20 | 0.85 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.85 |
| ▸ | CDK2 | P24941 | 5/20 | 0.85 |
| ▸ | SRC | P12931 | 3/20 | 0.85 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193120 | 1.00 | FLT3 (0.85) | FLT3PDGFRACDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL5196265 | 0.99 | FLT3 (0.84) | FLT3PDGFRACDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL5196269 | 0.99 | FLT3 (0.84) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL6949670 | 0.92 | PDGFRA (1.00) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL6949667 | 0.92 | PDGFRA (1.00) | FLT3PDGFRACDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6943536 | 0.91 | PDGFRA (0.98) | FLT3PDGFRACDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6943531 | 0.91 | PDGFRA (0.98) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL5193351 | 0.90 | PDGFRA (0.89) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL5193358 | 0.90 | PDGFRA (0.89) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL5195681 | 0.89 | FLT3 (0.78) | FLT3PDGFRACDK2SRCCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-B1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2007-08-22 | — | — | EP | claimed |
| JP-2003500407-A | — | — | 2003-01-07 | — | — | JP | claimed |
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | claimed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | claimed |
| EP-1737840-B1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-09-12 | — | — | EP | disclosed |
| EP-1183256-B1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2007-08-22 | — | — | EP | disclosed |
| EP-1737840-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005103033-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2005-11-03 | — | — | WO | disclosed |
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | disclosed |