Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 14/20 | 1.00 |
| ▸ | FLT3 | P36888 | 9/20 | 1.00 |
| ▸ | CDK2 | P24941 | 7/20 | 1.00 |
| ▸ | SRC | P12931 | 1/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.80 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.74 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.74 |
| ▸ | CDK1 | P06493 | 2/20 | 0.74 |
| ▸ | CDK4 | P11802 | 2/20 | 0.74 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.74 |
| ▸ | CCND1 | P24385 | 2/20 | 0.74 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949670 | 1.00 | PDGFRA (1.00) | PDGFRAFLT3CDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6943536 | 0.99 | PDGFRA (0.98) | PDGFRAFLT3CDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6943531 | 0.99 | PDGFRA (0.98) | PDGFRAFLT3CDK2SRCCCNE1 | |
| Acetonitrile SCHEMBL5196660 | 0.95 | PDGFRA (0.91) | PDGFRAFLT3CDK2SRCCCNE1 | |
| SCHEMBL5193358 | 0.94 | PDGFRA (0.89) | PDGFRAFLT3CDK2SRCCCNE1 | |
| SCHEMBL5193351 | 0.94 | PDGFRA (0.89) | PDGFRAFLT3CDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL5629614 | 0.93 | PDGFRA (0.87) | PDGFRAFLT3CDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL5626651 | 0.93 | PDGFRA (0.87) | PDGFRAFLT3CDK2SRCCCNE1 | |
| SCHEMBL5193120 | 0.92 | FLT3 (0.85) | PDGFRAFLT3CDK2SRCCCNE1 | |
| SCHEMBL5193129 | 0.92 | FLT3 (0.85) | PDGFRAFLT3CDK2SRCCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2003-10-22 | — | — | EP | claimed |