Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.47 |
| ▸ | F10 | P00742 | 5/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251466 | 0.95 | BDKRB1 (0.48) | BDKRB1F10KLK1 | |
| SCHEMBL5396927 | 0.90 | BDKRB1 (0.46) | BDKRB1MCHR1MCOLN3 | |
| SCHEMBL5393651 | 0.87 | BDKRB1 (0.47) | BDKRB1MCHR1MCOLN3 | |
| SCHEMBL5384936 | 0.84 | BDKRB1 (0.36) | BDKRB1F10KLK1 | |
| SCHEMBL5392291 | 0.82 | BDKRB1 (0.48) | BDKRB1MCHR1 | |
| SCHEMBL5118629 | 0.82 | BDKRB1 (0.54) | BDKRB1MCOLN3 | |
| SCHEMBL5382643 | 0.82 | BDKRB1 (0.69) | BDKRB1 | |
| SCHEMBL4036007 | 0.82 | BDKRB1 (0.71) | BDKRB1F10 | |
| Hydrochloric Acid SCHEMBL5385888 | 0.81 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL5216063 | 0.81 | BDKRB1 (0.44) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812405-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048209-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |