Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195761 | 0.92 | BDKRB1 (0.39) | BDKRB1DRD2DRD4DRD3 | |
| SCHEMBL5219687 | 0.91 | BDKRB1 (0.39) | BDKRB1DRD2DRD4DRD3STS | |
| SCHEMBL5392291 | 0.89 | BDKRB1 (0.48) | BDKRB1DRD2DRD4DRD3STS | |
| SCHEMBL5251466 | 0.85 | BDKRB1 (0.48) | BDKRB1DRD2DRD4DRD3 | |
| SCHEMBL5393651 | 0.84 | BDKRB1 (0.47) | BDKRB1DRD2DRD4DRD3STS | |
| SCHEMBL5194763 | 0.83 | BDKRB1 (0.33) | BDKRB1 | |
| SCHEMBL5402639 | 0.82 | BDKRB1 (0.42) | BDKRB1DRD2DRD4DRD3STS | |
| SCHEMBL5390404 | 0.81 | BDKRB1 (0.41) | BDKRB1DRD2DRD4DRD3STS | |
| SCHEMBL5377553 | 0.81 | BDKRB1 (0.43) | BDKRB1DRD2DRD4DRD3STS | |
| SCHEMBL5193350 | 0.81 | BDKRB1 (0.47) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812405-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048209-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |