Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 11/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.62 |
| ▸ | CDK2 | P24941 | 10/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.62 |
| ▸ | CDK1 | P06493 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193482 | 0.89 | CDK5 (0.60) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL5827777 | 0.88 | CDK5 (0.79) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL5193842 | 0.87 | CDK5 (0.80) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL5196875 | 0.85 | CDK1 (0.83) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL5196103 | 0.83 | CDK5 (0.53) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL5626927 | 0.81 | CDK5 (0.63) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL5196519 | 0.80 | CDK1 (0.55) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL3379300 | 0.80 | YTHDC1 (0.60) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL183230 | 0.78 | CDK1 (0.66) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL17628619 | 0.78 | YTHDC1 (0.57) | CDK5CDK5R1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183256-B1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2007-08-22 | — | — | EP | disclosed |
| EP-1377260-B1 | HAIR FIXATIVE COMPOSITION CONTAINING AN ANIONIC POLYMER | ONDEO NALCO CO (US) | 2007-06-27 | — | — | EP | disclosed |
| US-7208598-B2 | Derivatives of purine, their preparation process and pharmaceutical compositions containing them | AVENTIS PHARMA (FR) | 2007-04-24 | — | — | US | disclosed |
| EP-1488774-B1 | Polymer compositions and processes for preparing polymers | ROHM & HAAS (US) | 2007-03-14 | — | — | EP | disclosed |
| US-7160970-B2 | Process for manufacturing polymers | ROHM AND HAAS COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7122669-B1 | Purine derivatives, preparation method and pharmaceutical compositions containing same | HOECHST MARION ROUSSEL (FR) | 2006-10-17 | — | — | US | disclosed |
| US-20050187228-A1 | Derivatives of purine, their preparation process and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. | 2005-08-25 | — | — | US | disclosed |
| US-20050107546-A1 | Process for manufacturing polymers | ROHM AND HAAS COMPANY | 2005-05-19 | — | — | US | disclosed |
| EP-1530962-A1 | Process for manufacturing polymers | ROHM AND HAAS COMPANY (US) | 2005-05-18 | — | — | EP | disclosed |
| US-20040258648-A1 | Polymer compositions and process for preparing polymers | CREAMER MARIANNE PATRICIA (US) | 2004-12-23 | — | — | US | disclosed |
| EP-1488774-A2 | Polymer compositions and processes for preparing polymers | ROHM AND HAAS COMPANY (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1377260-A4 | HAIR FIXATIVE COMPOSITION CONTAINING AN ANIONIC POLYMER | ONDEO NALCO CO (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1377260-A1 | HAIR FIXATIVE COMPOSITION CONTAINING AN ANIONIC POLYMER | Ondeo Nalco Company (US) | 2004-01-07 | — | — | EP | disclosed |
| US-6569413-B1 | Anionic copolymer of 2-acrylamido-2-methyl-1-propanesulfonic acid | ONDEO NALCO COMPANY | 2003-05-27 | — | — | US | disclosed |
| WO-2002083089-A1 | HAIR FIXATIVE COMPOSITION CONTAINING AN ANIONIC POLYMER | ONDEO NALCO COMPANY (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-1183256-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071543-A1 | PURINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2000-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187228-A1 | Derivatives of purine, their preparation process and pharmaceutical compositions containing them | CDK6, CDK1, CDK2 | CDK5 15/4885CDK5R1 51/4885CDK2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.