Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MDH2 | P40926 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163027 | 0.76 | HTT (0.49) | HTTALDH1A1HPGDMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5196509 | 0.74 | GABRA1 (0.51) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| Trifluoroacetic Acid SCHEMBL3815626 | 0.69 | KDM4E (0.59) | HTTALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5191003 | 0.68 | HTT (0.47) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5191036 | 0.68 | GABRA1 (0.59) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL3646574 | 0.67 | HTT (0.51) | HTTALDH1A1HPGDMEN1KMT2A | |
| Formic Acid SCHEMBL5161456 | 0.66 | HTT (0.44) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2971723 | 0.66 | KDM4E (0.56) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11022445 | 0.65 | KDM4E (0.55) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9424983 | 0.65 | KDM4E (0.64) | HTTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756135-A1 | ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005108412-A1 | ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) | 2005-11-17 | — | — | WO | disclosed |