Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 known ✓ | P08588 | 6/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5582900 | 0.94 | ADRB2 (0.68) | ADRB2ADRB1 | |
| Fumaric Acid SCHEMBL5190364 | 0.92 | ADRB2 (0.60) | ADRB2ADRB1 | |
| SCHEMBL4283475 | 0.88 | ADRB2 (0.63) | ADRB2ADRB1 | |
| SCHEMBL5165194 | 0.88 | ADRB2 (0.65) | ADRB2ADRB1 | |
| SCHEMBL2784953 | 0.87 | ADRB2 (0.61) | ADRB2ADRB1 | |
| SCHEMBL3634485 | 0.86 | ADRB2 (0.55) | ADRB2ADRB1 | |
| SCHEMBL5189304 | 0.86 | ADRB2 (0.62) | ADRB2ADRB1 | |
| Fumaric Acid SCHEMBL5582503 | 0.85 | ADRB2 (0.59) | ADRB2ADRB1 | |
| SCHEMBL5192822 | 0.85 | ADRB2 (0.70) | ADRB2ADRB1 | |
| SCHEMBL3649801 | 0.85 | ADRB2 (0.70) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809236-A1 | INHALATION POWDER FORMULATIONS CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2005110359-A1 | INHALATION POWDER FORMULATIONS CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |