Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021888 | 0.88 | SLC6A2 (0.58) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| Malonic Acid SCHEMBL5194387 | 0.88 | SLC6A3 (0.51) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL1023293 | 0.87 | SLC6A2 (0.57) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL6217469 | 0.78 | SLC6A2 (0.38) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL7806031 | 0.76 | SLC6A4 (0.80) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| Fumaric Acid SCHEMBL5194238 | 0.76 | SLC6A2 (0.52) | SLC6A4SLC6A3SLC6A2KMT2AOPRM1 | |
| Fumaric Acid SCHEMBL5194245 | 0.76 | SLC6A2 (0.52) | SLC6A4SLC6A3SLC6A2KMT2AOPRM1 | |
| SCHEMBL5829525 | 0.75 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2HTR6ALDH1A1 | |
| SCHEMBL6553385 | 0.75 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2HTR6ALDH1A1 | |
| SCHEMBL7809824 | 0.75 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859777-B1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH AS (DK) | 2007-05-23 | — | — | EP | disclosed |
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | disclosed |
| US-6100275-A | SEROTONIN RE-UPTAKE INHIBITORS; ANTIDEPRESSANTS | NEUROSEARCH A/S (DK) | 2000-08-08 | — | — | US | disclosed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | disclosed |
| CN-1199400-A | 8-azabicyclo [3.2.1] oct-2-ene derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1998-11-18 | — | — | CN | disclosed |
| EP-0859777-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997013770-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1997-04-17 | — | — | WO | disclosed |