Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 19/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191876 | 0.99 | PYGL (0.62) | PYGLCYP2C9IDO1 | |
| Hydrochloric Acid SCHEMBL5192284 | 0.97 | PYGL (0.61) | PYGLCYP2C9IDO1 | |
| SCHEMBL5195809 | 0.90 | PYGL (0.50) | PYGLCYP2C9IDO1 | |
| SCHEMBL5422892 | 0.88 | PYGL (0.49) | PYGLCYP2C9IDO1 | |
| Hydrochloric Acid SCHEMBL5196178 | 0.88 | PYGL (0.59) | PYGLCYP2C9IDO1 | |
| Hydrochloric Acid SCHEMBL5211970 | 0.88 | PYGL (0.59) | PYGLCYP2C9 | |
| Hydrochloric Acid SCHEMBL5211974 | 0.88 | PYGL (0.59) | PYGLCYP2C9 | |
| Hydrochloric Acid SCHEMBL5211964 | 0.88 | PYGL (0.59) | PYGLCYP2C9 | |
| SCHEMBL5423321 | 0.87 | PYGL (0.62) | PYGLCYP2C9IDO1 | |
| SCHEMBL5196089 | 0.87 | PYGL (0.61) | PYGLCYP2C9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812383-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | Smithkline Beecham Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006052722-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-18 | — | — | WO | disclosed |