Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587784 | 0.84 | ACHE (0.54) | SLC6A4TSHRCA12CA1CA2 | |
| SCHEMBL9587777 | 0.84 | ACHE (0.47) | SLC6A4CYP2C19MAPTHIF1AALDH1A1 | |
| SCHEMBL29378424 | 0.84 | ACHE (0.50) | SLC6A4CYP2C19CA1CA2MAPK1 | |
| SCHEMBL4861715 | 0.82 | SLC6A4 (0.63) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10603367 | 0.82 | SLC6A4 (0.63) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22060049 | 0.80 | TSHR (0.58) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4936291 | 0.79 | SLC6A4 (0.60) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25666938 | 0.78 | SLC6A4 (0.55) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20543172 | 0.77 | TSHR (0.58) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3753646 | 0.77 | TSHR (0.58) | SLC6A4TSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799634-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |