SCHEMBL5194302

SCHEMBL5194302

CCC(CC)c1cc(C)nn2c(-c3sc(-c4cccc(CC=O)n4)cc3C)c(C)nc12

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 3/20 0.49
CRHR2 Q13324 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3929392 0.91 CRHR1 (0.52) CRHR1CRHR2
SCHEMBL3921459 0.88 CRHR1 (0.55) CRHR1CRHR2
Hydrochloric Acid SCHEMBL3931247 0.87 CRHR1 (0.54) CRHR1CRHR2
SCHEMBL3922580 0.85 CRHR1 (0.52) CRHR1CRHR2
SCHEMBL3923487 0.84 CRHR1 (0.49) CRHR1CRHR2
SCHEMBL3922582 0.84 CRHR1 (0.49) CRHR1CRHR2
SCHEMBL3924599 0.84 CRHR1 (0.51) CRHR1CRHR2
SCHEMBL3925936 0.84 CRHR1 (0.51) CRHR1CRHR2
SCHEMBL3923236 0.83 CRHR1 (0.52) CRHR1CRHR2
SCHEMBL3924631 0.83 CRHR1 (0.53) CRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869049-A1 IMIDAZOPYRIDAZINE COMPOUNDS ELI LILLY AND COMPANY (US) 2007-12-26 EP disclosed
WO-2006102194-A1 IMIDAZOPYRIDAZINE COMPOUNDS ELI LILLY AND COMPANY (US) 2006-09-28 WO disclosed