Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190326 | 0.95 | NOS2 (0.43) | NOS2 | |
| SCHEMBL5191910 | 0.93 | NOS2 (0.48) | NOS2 | |
| SCHEMBL5191168 | 0.92 | NOS2 (0.45) | NOS2 | |
| SCHEMBL5193012 | 0.92 | NOS2 (0.45) | NOS2 | |
| SCHEMBL5190389 | 0.90 | NOS2 (0.45) | NOS2 | |
| SCHEMBL5192239 | 0.90 | NOS2 (0.46) | NOS2 | |
| SCHEMBL5190381 | 0.90 | NOS2 (0.48) | NOS2 | |
| SCHEMBL5194400 | 0.90 | NOS2 (0.42) | NOS2 | |
| SCHEMBL6835097 | 0.89 | NOS2 (0.43) | NOS2 | |
| SCHEMBL5194687 | 0.89 | NOS2 (0.47) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| EP-0968206-B1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LAB (US) | 2006-11-15 | — | — | EP | disclosed |