Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184904 | 1.00 | SIGMAR1 (0.40) | SIGMAR1HTR6HTR2AMAOAMAOB | |
| SCHEMBL5888461 | 0.86 | HTR2A (0.41) | SIGMAR1HTR6HTR2AALDH1A1HPGD | |
| SCHEMBL29645065 | 0.86 | HTR2A (0.41) | SIGMAR1HTR6HTR2AALDH1A1HPGD | |
| SCHEMBL29633478 | 0.84 | HTR2A (0.40) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 | |
| Bromide SCHEMBL7531587 | 0.84 | HTR2A (0.40) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 | |
| Fluoride SCHEMBL7560410 | 0.84 | HTR2A (0.40) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1929585 | 0.84 | HTR2A (0.40) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4855724 | 0.84 | HTR2A (0.40) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 | |
| Methyl Alcohol SCHEMBL5277893 | 0.80 | HTR2A (0.38) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL8155328 | 0.79 | HTR2A (0.38) | SIGMAR1HTR6HTR2AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737893-A1 | PHOSPHORUS BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005108435-A1 | PHOSPHORUS BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-11-17 | — | — | WO | claimed |