Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119262 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL4687 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL8532996 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL5835621 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL338191 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL5544656 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL4291 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL6374631 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL8192290 | 0.91 | GRM5 (0.49) | GRM5CYP2D6CA2 | |
| SCHEMBL27504027 | 0.90 | GRM5 (0.48) | GRM5CYP2D6CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756049-A1 | METHOD FOR PRODUCING 1,4-DIPHENYL AZETIDINONE DERIVATIVES | Sanofi-Aventis Deutschland GmbH (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005113496-A1 | METHOD FOR PRODUCING 1,4-DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (US) | 2005-12-01 | — | — | WO | disclosed |