Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 18/20 | 0.59 |
| ▸ | GGPS1 | O95749 | 9/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370583 | 0.97 | FDPS (0.62) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL5196818 | 0.79 | FDPS (0.59) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL10606739 | 0.76 | FDPS (0.46) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL594692 | 0.74 | FDPS (1.00) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL9296429 | 0.74 | FDPS (0.83) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL601974 | 0.73 | — | — | |
| SCHEMBL10773437 | 0.73 | FDPS (0.48) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL252754 | 0.73 | FDPS (0.48) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL10700377 | 0.72 | FDPS (0.95) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL24616673 | 0.71 | FDPS (0.68) | FDPSGGPS1PDE3ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848727-A1 | IBANDRONATE POLYMORPH B | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-31 | — | — | EP | claimed |
| WO-2006081962-A1 | IBANDRONATE POLYMORPH B | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | claimed |
| EP-1848727-A1 | IBANDRONATE POLYMORPH B | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| EP-1848728-A1 | IBANDRONATE POLYMORPH A | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006081963-A1 | IBANDRONATE POLYMORPH A | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006081962-A1 | IBANDRONATE POLYMORPH B | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | disclosed |