Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 8/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985134 | 0.89 | LMNA (0.46) | LMNAMAPK1RAB9ACYP3A4ERN1 | |
| SCHEMBL9191402 | 0.85 | LMNA (0.42) | LMNAMAPK1RAB9ACYP3A4ERN1 | |
| SCHEMBL1712987 | 0.78 | TSHR (0.48) | LMNATSHRALDH1A1MAPT | |
| SCHEMBL8924794 | 0.78 | LMNA (0.42) | LMNAMAPK1RAB9ACYP3A4ERN1 | |
| SCHEMBL4195614 | 0.76 | LMNA (0.46) | LMNAMAPK1RAB9ACYP3A4ERN1 | |
| SCHEMBL3992214 | 0.74 | LMNA (0.45) | LMNAMAPK1RAB9ACYP3A4ERN1 | |
| SCHEMBL3997516 | 0.74 | LMNA (0.45) | LMNAMAPK1RAB9ACYP3A4ERN1 | |
| SCHEMBL1713224 | 0.74 | NOTUM (0.34) | TSHR | |
| SCHEMBL1713612 | 0.74 | SMN1; SMN2 (0.42) | LMNATSHRALDH1A1MAPT | |
| SCHEMBL30564477 | 0.73 | LMNA (0.40) | LMNAMAPK1RAB9ACYP3A4ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067131-B1 | New process for the manufacture of cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2007-08-15 | — | — | EP | claimed |
| US-6384214-B1 | ALKALINE CONVERSION OF PYRROLIDINYL PHOSHONIUM SALT TO YLIDE FOLLOWED BY COUPLING WITH A 5-THIA-1-AZABICYCLOOCTANE 2-ALDEHYDE; ISOMERIZATION INHIBITION | BASILEA PHARMACEUTICA AG (CH) | 2002-05-07 | — | — | US | claimed |
| EP-1067131-A1 | New process for the manufacture of cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-01-10 | — | — | EP | claimed |
| EP-1067131-B1 | New process for the manufacture of cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-6384214-B1 | ALKALINE CONVERSION OF PYRROLIDINYL PHOSHONIUM SALT TO YLIDE FOLLOWED BY COUPLING WITH A 5-THIA-1-AZABICYCLOOCTANE 2-ALDEHYDE; ISOMERIZATION INHIBITION | BASILEA PHARMACEUTICA AG (CH) | 2002-05-07 | — | — | US | disclosed |
| EP-1067131-A1 | New process for the manufacture of cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0330108-B1 | 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5081237-A | Chemical intermediates for bactericides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4923857-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0330108-A1 | 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |