Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823153 | 0.82 | NR3C1 (0.42) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL6755263 | 0.82 | NR3C1 (0.42) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL7113336 | 0.82 | NR3C1 (0.42) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL14108981 | 0.80 | CYP19A1 (0.37) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL5199219 | 0.75 | NR3C1 (0.33) | CYP19A1NR3C1 | |
| SCHEMBL14084990 | 0.74 | NR3C1 (0.41) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL6753119 | 0.72 | NR3C1 (0.41) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL4815312 | 0.72 | NR3C1 (0.41) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL6706204 | 0.69 | NR3C1 (0.42) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL6755244 | 0.69 | AR (0.34) | CYP19A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539795-B1 | CRYSTALLINE 17BETA-HYDROXY-7ALPHA-(5'-METHYL-2'-FURYL)-PREGNA-4,9(11)-DIEN-3-ONE-21-CARBOXYLIC ACID, GAMMA-LACTONE | PHARMACIA & UPJOHN CO LLC (US) | 2007-10-31 | — | — | EP | disclosed |