Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 7/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200226 | 0.85 | FABP4 (0.43) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5198855 | 0.82 | TEK (0.44) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5198874 | 0.81 | TEK (0.42) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5198712 | 0.81 | TEK (0.48) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| Methyl Alcohol SCHEMBL27727314 | 0.81 | FABP4 (0.53) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5197690 | 0.81 | MAPK14 (0.44) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5197084 | 0.80 | TEK (0.46) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5194034 | 0.79 | TEK (0.42) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5194709 | 0.78 | TEK (0.39) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5196849 | 0.78 | TEK (0.40) | TEKMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846389-A1 | IMIDAZOLE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2007-10-24 | — | — | EP | claimed |
| WO-2006082002-A1 | IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | claimed |