Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196821 | 0.85 | FFAR1 (0.48) | CA1CA2HIF1A | |
| SCHEMBL16230241 | 0.80 | APP (0.41) | SMN1; SMN2PTPRBCA1CA2CA9 | |
| SCHEMBL14622141 | 0.78 | JAK3 (0.56) | JAK3POLBSMN1; SMN2HTTKMT2A | |
| SCHEMBL693860 | 0.75 | SLC7A5 (0.54) | SMN1; SMN2LMNAHTTKMT2AUSP2 | |
| SCHEMBL10131967 | 0.75 | NEK2 (0.43) | POLBSMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL3104224 | 0.75 | NR1H4 (0.56) | FABP4KMT2ANR1H4SELPSELE | |
| SCHEMBL14148255 | 0.73 | CSNK2A1 (0.48) | POLBSMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL2636349 | 0.72 | HTT (0.45) | SMN1; SMN2LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL3295049 | 0.72 | NEK2 (0.43) | NR3C1HTR6 | |
| SCHEMBL14355361 | 0.72 | ALDH1A1 (0.41) | LMNAPTPRBALDH1A1HTR6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868983-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006087166-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2006-08-24 | — | — | WO | disclosed |