Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431103 | 0.79 | — | — | |
| SCHEMBL427806 | 0.77 | — | — | |
| SCHEMBL27848691 | 0.72 | — | — | |
| SCHEMBL5933426 | 0.69 | — | — | |
| SCHEMBL6656837 | 0.69 | — | — | |
| SCHEMBL28047502 | 0.68 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL27578572 | 0.68 | USP2 (0.33) | USP2SMN1; SMN2ELANE | |
| SCHEMBL4434089 | 0.67 | HPGD (0.39) | USP2SMN1; SMN2ELANE | |
| SCHEMBL28288528 | 0.67 | NAAA (0.41) | SMN1; SMN2 | |
| Bromide SCHEMBL29204822 | 0.67 | HTT (0.32) | HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812405-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048209-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |