Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197713 | 0.94 | MEN1 (0.32) | MEN1KMT2ATDP1UPP1ALDH1A1 | |
| SCHEMBL5199373 | 0.87 | UPP1 (0.45) | MEN1KMT2ATSHRTDP1UPP1 | |
| SCHEMBL5199239 | 0.87 | UPP1 (0.44) | UPP1HTT | |
| SCHEMBL5198534 | 0.85 | UPP1 (0.38) | MEN1KMT2ATDP1UPP1ALDH1A1 | |
| SCHEMBL2107018 | 0.84 | SMN1; SMN2 (0.36) | MEN1KMT2ATDP1UPP1ALDH1A1 | |
| SCHEMBL5199124 | 0.84 | UPP1 (0.37) | UPP1 | |
| SCHEMBL7256071 | 0.83 | ALDH1A1 (0.32) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5200101 | 0.83 | SMN1; SMN2 (0.34) | MEN1KMT2ATDP1UPP1ALDH1A1 | |
| SCHEMBL7254871 | 0.82 | ALDH1A1 (0.32) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6304553 | 0.82 | KMT2A (0.37) | MEN1KMT2ATDP1UPP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355887-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIV GENEVE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-6911450-B1 | Pyrimidine acyclonucleoside derivatives, preparation method and use thereof | UNIVERSITE DE GENEVE (CH) | 2005-06-28 | — | — | US | disclosed |
| EP-1355887-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIVERSITE DE GENEVE (CH) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002060880-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIVERSITE DE GENEVE (CH) | 2002-08-08 | — | — | WO | disclosed |