Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.70 |
| ▸ | DRD4 | P21917 | 7/20 | 0.70 |
| ▸ | DRD3 | P35462 | 6/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198644 | 0.83 | DRD4 (0.71) | DRD2DRD4DRD3CYP2D6HTR6 | |
| SCHEMBL5199492 | 0.81 | DRD2 (0.67) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL14281102 | 0.78 | DRD4 (0.80) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL5196816 | 0.78 | DRD2 (0.71) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL5196341 | 0.78 | DRD2 (0.63) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL22619024 | 0.77 | DRD2 (0.63) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL5197511 | 0.77 | DRD2 (0.61) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL5199113 | 0.76 | DRD2 (0.66) | DRD2DRD4DRD3CYP2D6BCHE | |
| SCHEMBL5198777 | 0.76 | DRD2 (0.67) | DRD2DRD4DRD3CYP2D6L3MBTL1 | |
| SCHEMBL23964192 | 0.76 | DRD4 (0.80) | DRD2DRD4DRD3CYP2D6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815866-A1 | REMEDY OR PREVENTIVE FOR ISCHEMIC CARDIAC DISEASE OR ISCHEMIC CARDIAC MYOPATHY | Neugen Pharma, Inc (JP) | 2007-08-08 | — | — | EP | disclosed |