Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358758 | 0.83 | GSR (0.58) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL8138 | 0.83 | GSR (0.58) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL154380 | 0.83 | GSR (0.58) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL31562940 | 0.79 | GSR (0.62) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Phosphoric Acid SCHEMBL8519189 | 0.77 | GRM8 (0.50) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL8587639 | 0.77 | PMP22 (0.52) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL11215138 | 0.77 | GSR (0.60) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL10135850 | 0.77 | GSR (0.60) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamine Hydroxamate SCHEMBL4321249 | 0.77 | GSR (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamine Hydroxamate SCHEMBL7645305 | 0.77 | GSR (0.67) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017032798-A1 | NOVEL INSULIN DERIVATIVES AND THE MEDICAL USES HEREOF | NOVO NORDISK A/S (DK) | 2017-03-02 | — | — | WO | disclosed |
| EP-1752143-A1 | Novel uses for drugs targeting glutamine synthetase | NewThera (FR) | 2007-02-14 | — | — | EP | disclosed |