SCHEMBL8138

SCHEMBL8138

CNC(=O)CCC(N)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.58
GRM8 O00222 1/20 0.58
GRM6 O15303 1/20 0.58
GRIN2D O15399 1/20 0.58
GRIN3B O60391 1/20 0.58
CYP1A2 P05177 1/20 0.58
GRIK1 P39086 1/20 0.58
GRM5 P41594 1/20 0.58
GRIA1 P42261 1/20 0.58
GRIA2 P42262 1/20 0.58
GRIA3 P42263 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58
SLC1A1 P43005 1/20 0.58
GRIA4 P48058 1/20 0.58
GRIN1 Q05586 1/20 0.58
GRIN2A Q12879 1/20 0.58
GRIK2 Q13002 1/20 0.58
GRIK3 Q13003 1/20 0.58
GRIN2B Q13224 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154380 1.00 GSR (0.58) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL358758 1.00 GSR (0.58) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL8587639 0.92 PMP22 (0.52) GSRGRM8GRM6GRIN2DGRIN3B
Phosphoric Acid SCHEMBL8519189 0.92 GRM8 (0.50) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL14423586 0.88 GSR (0.50) GSRGRM8GRM6GRIN2DGRIN3B
Lysine SCHEMBL4561856 0.88 GSR (0.67) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL19774715 0.87 SLC1A1 (0.48) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL22186668 0.85 GRM8 (0.56) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL5198612 0.83 GRM8 (0.54) GSRGRM8GRM6GRIN2DGRIN3B
SCHEMBL1769601 0.83 OTC (0.45) GSRGRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161408-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2025-05-22 US claimed
CN-115927217-B Gamma-glutamylmethylamine synthetase mutant and application thereof 河北远大九孚生物科技有限公司 2025-02-18 CN claimed
EP-4482852-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY Technische Universität München (DE) 2025-01-01 EP claimed
EP-4295866-A2 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS Virometix AG (CH) 2023-12-27 EP claimed
WO-2023161211-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY Technische Universität München (DE) 2023-08-31 WO claimed
EP-3638284-B1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS VIROMETIX AG (CH) 2023-08-30 EP claimed
EP-4230645-A1 PEPTIDIC INHIBITORS OF AMYLOID SELF- AND CROSS-ASSEMBLY Technische Universität München (DE) 2023-08-23 EP claimed
US-11680085-B2 Cyclic peptides for protection against respiratory syncytial virus VIROMETIX AG (CH) 2023-06-20 US claimed
CN-113151198-B Gamma-glutamine synthetase mutant, coding gene, amino acid sequence and application thereof 大连医诺生物股份有限公司 2023-04-11 CN claimed
CN-113151199-B Gamma-glutamine synthetase mutant with thermal stability, coding gene, amino acid sequence and application thereof 大连医诺生物股份有限公司 2023-04-11 CN claimed
EP-2097065-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS Foamix Ltd. (IL) 2009-09-09 EP claimed
WO-2008152444-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS FOAMIX LTD. (US) 2008-12-18 WO claimed
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions FOAMIX LTD. (IL) 2008-08-28 US claimed
EP-1411965-A4 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION NOVACTYL INC (US) 2006-01-11 EP claimed
EP-1411965-A1 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION Novactyl, Inc. (US) 2004-04-28 EP claimed
WO-2003006044-A1 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION NOVACTYL, INC. (US) 2003-01-23 WO claimed
US-20020037908-A1 Methods and compositions for controlling protein assembly or aggregation NOVACTYL, INC. 2002-03-28 US claimed
US-5302604-A Squalene synthetase inhibitors, anticarcinogenic agents, zaragozic acid derivatives MERCK & CO., INC. (US) 1994-04-12 US claimed
US-5294627-A Anticholesterol MERCK & CO., INC. (US) 1994-03-15 US claimed
WO-1993017557-A1 CHOLESTEROL LOWERING COMPOUNDS PRODUCED BY DIRECTED BIOSYNTHESIS MERCK & CO., INC. (US) 1993-09-16 WO claimed