Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054843 | 0.85 | CHRM2 (0.43) | IDO1TDO2KMT2AMEN1ADRB2 | |
| SCHEMBL580492 | 0.83 | CHRM2 (0.46) | KMT2AMEN1ADRB2CHRM2CHRM1 | |
| SCHEMBL579637 | 0.83 | CHRM2 (0.46) | KMT2AMEN1ADRB2CHRM2CHRM1 | |
| SCHEMBL579976 | 0.83 | CHRM2 (0.46) | KMT2AMEN1ADRB2CHRM2CHRM1 | |
| SCHEMBL5198568 | 0.82 | NPSR1 (0.47) | KMT2AMEN1CHRM2CHRM1MAPK1 | |
| SCHEMBL13761466 | 0.81 | ADRB2 (0.45) | IDO1TDO2KMT2AMEN1ADRB2 | |
| SCHEMBL580391 | 0.80 | NPSR1 (0.48) | KMT2AMEN1CHRM2CHRM1MAPK1 | |
| SCHEMBL579842 | 0.79 | MEN1 (0.47) | KMT2AMEN1ADRB2CHRM2CHRM1 | |
| SCHEMBL580162 | 0.79 | MEN1 (0.47) | KMT2AMEN1ADRB2CHRM2CHRM1 | |
| SCHEMBL580371 | 0.79 | MEN1 (0.47) | KMT2AMEN1ADRB2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633695-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1633695-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | Bridge Pharma, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105692-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA, INC. (US) | 2004-12-09 | — | — | WO | disclosed |