SCHEMBL5199683

SCHEMBL5199683

CC1=CCC2(CCCC(C)(C)C2CC(=O)O)C(C)C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
NR1I2 O75469 1/20 0.32
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24475288 0.76 CYP3A4 (0.33)
SCHEMBL5199050 0.76 CYP3A4 (0.33)
Acetic Acid SCHEMBL30441222 0.75
SCHEMBL5200052 0.75 CYP3A4 (0.34) ESR1NR1I2HSD11B1
SCHEMBL21035809 0.75 CYP3A4 (0.34) ESR1NR1I2HSD11B1
SCHEMBL30442155 0.75 CYP3A4 (0.34) ESR1NR1I2HSD11B1
SCHEMBL5201767 0.72
SCHEMBL22614807 0.68 UGT2B7 (0.32)
SCHEMBL22614817 0.67 UGT2B7 (0.31)
SCHEMBL21001226 0.67 TRPA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411110-B1 Spiro compounds as perfuming ingredients FIRMENICH & CIE (CH) 2007-08-22 EP claimed
US-12024690-B2 Method of countering malodour in a washing machine comprising the addition of a fragrance precursor accord comprising 4-(dodecylthio)-4-methylpentan-2-one GIVAUDAN SA (CH) 2024-07-02 US disclosed