Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 18/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198212 | 0.84 | TGFBR1 (0.41) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5198303 | 0.83 | TGFBR1 (0.40) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5198402 | 0.83 | TGFBR1 (0.43) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5199982 | 0.81 | TGFBR1 (0.39) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5199237 | 0.80 | TGFBR1 (0.39) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5198453 | 0.80 | TGFBR1 (0.39) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5201354 | 0.79 | TGFBR1 (0.46) | TGFBR1 | |
| SCHEMBL5492614 | 0.78 | TGFBR1 (0.58) | TGFBR1 | |
| SCHEMBL5199536 | 0.77 | TGFBR1 (0.38) | TGFBR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5199509 | 0.77 | TGFBR1 (0.38) | TGFBR1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798229-A1 | SUBSTITUTED BIPHENYL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |