Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.37 |
| ▸ | CTSD | P07339 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13108399 | 0.86 | CYSLTR1 (0.54) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL13108391 | 0.86 | CYSLTR1 (0.54) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL481199 | 0.86 | CYSLTR1 (0.54) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL481076 | 0.78 | CYSLTR1 (0.55) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL27686243 | 0.78 | GRM2 (0.36) | MAPTCYSLTR1GRM2 | |
| SCHEMBL480949 | 0.77 | CYSLTR1 (0.54) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL481066 | 0.76 | CYSLTR1 (0.53) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL481219 | 0.76 | GRM2 (0.52) | MAPTCYSLTR1CYSLTR2GRM2 | |
| SCHEMBL481160 | 0.75 | CYSLTR1 (0.52) | MEN1TSHRKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL27686236 | 0.75 | GRM2 (0.38) | MAPTCYSLTR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817301-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006057870-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |