⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201286 | 0.76 | CA1 (0.34) | — | |
| SCHEMBL8761091 | 0.75 | POLB (0.38) | — | |
| SCHEMBL969497 | 0.70 | — | — | |
| SCHEMBL4319991 | 0.70 | — | — | |
| SCHEMBL1118760 | 0.70 | — | — | |
| SCHEMBL9060357 | 0.70 | — | — | |
| SCHEMBL9704744 | 0.70 | — | — | |
| SCHEMBL2883798 | 0.69 | — | — | |
| SCHEMBL7309137 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL1007115 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1798229-A1 | SUBSTITUTED BIPHENYL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |