Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197738 | 0.91 | SIGMAR1 (0.57) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5198814 | 0.89 | SIGMAR1 (0.55) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5907033 | 0.89 | SIGMAR1 (0.59) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5200298 | 0.86 | SIGMAR1 (0.56) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5197569 | 0.84 | SIGMAR1 (0.54) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL9705744 | 0.80 | SIGMAR1 (0.68) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5906981 | 0.79 | SIGMAR1 (0.55) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL6500245 | 0.79 | SIGMAR1 (0.73) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL5906998 | 0.78 | SIGMAR1 (0.53) | SIGMAR1POLBL3MBTL1 | |
| SCHEMBL13360982 | 0.78 | SIGMAR1 (0.75) | SIGMAR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567495-A4 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | HARVARD COLLEGE (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060159617-A1 | Small technetium-99m and rhenium labeled agents and methods for imaging tissues, organs and tumors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-07-20 | — | — | US | disclosed |
| EP-1567495-A2 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004043380-A2 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060159617-A1 | Small technetium-99m and rhenium labeled agents and methods for imaging tissues, organs and tumors | SSTR5, SSTR1, SSTR3 | SIGMAR1 304/4885POLB 4630/4885L3MBTL1 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.