Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684308 | 0.81 | PDE10A (0.43) | PDE10AALDH1A1RAB9AGRM4SMN1; SMN2 | |
| SCHEMBL7605126 | 0.79 | KDM4E (0.41) | ALDH1A1RAB9AMEN1KMT2APARP1 | |
| SCHEMBL1767096 | 0.79 | RAB9A (0.41) | ALDH1A1RAB9AMEN1KMT2APARP1 | |
| SCHEMBL5206688 | 0.79 | RAB9A (0.41) | ALDH1A1RAB9AMEN1KMT2APARP1 | |
| SCHEMBL29119695 | 0.78 | PLAU (0.51) | MEN1KMT2AGRM4PARP1KDM4E | |
| SCHEMBL4081448 | 0.78 | RAB9A (0.40) | ALDH1A1RAB9AMEN1KMT2APARP1 | |
| SCHEMBL28683997 | 0.78 | PLAU (0.44) | RAB9AMEN1KMT2APARP1SMN1; SMN2 | |
| SCHEMBL15880497 | 0.78 | HTT (0.42) | ALDH1A1RAB9AMEN1KMT2APARP1 | |
| SCHEMBL28793465 | 0.78 | RAB9A (0.46) | ALDH1A1RAB9AMEN1KMT2APARP1 | |
| SCHEMBL29230750 | 0.78 | RAB9A (0.40) | PDE10AALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624191-A | Indazole carboxamide derivatives, preparation method and application thereof | 熙源安健医药（上海）有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117466893-A | Pyridocycloheptane derivative and preparation method and application thereof | 熙源安健医药（上海）有限公司 | 2024-01-30 | — | — | CN | disclosed |
| EP-2603513-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020848-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-16 | — | — | WO | disclosed |
| EP-1814871-A2 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006053791-A2 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-05-26 | — | — | WO | disclosed |