Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.45 |
| ▸ | PGR | P06401 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818905 | 0.90 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL4818900 | 0.90 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL4818910 | 0.90 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL5201174 | 0.89 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL5203051 | 0.81 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL5202396 | 0.80 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL4817619 | 0.80 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL4817615 | 0.80 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL4817624 | 0.80 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL6404891 | 0.79 | NR3C1 (0.52) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |