Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 13/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549824 | 0.83 | FBP1 (0.58) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL4467143 | 0.82 | FBP1 (0.53) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL3904657 | 0.81 | FBP1 (0.52) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL1549946 | 0.81 | PPARA (0.48) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL3585865 | 0.81 | FBP1 (0.60) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL1550089 | 0.80 | PPARA (0.50) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL3922298 | 0.80 | PPARA (0.47) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL6698511 | 0.76 | PPARA (0.46) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL14110348 | 0.75 | FBP1 (0.46) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL5098595 | 0.74 | PPARA (0.45) | PPARACYP1A2ABCB11CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | disclosed |