Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16042097 | 0.90 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL27799099 | 0.86 | TK1 (0.41) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL1825757 | 0.79 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL28129115 | 0.79 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL3477 | 0.79 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL12658380 | 0.79 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8904559 | 0.79 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL28189821 | 0.79 | TK1 (0.41) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL28207939 | 0.79 | TYMP (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL29041599 | 0.78 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819718-A1 | DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF | Sicor Inc. (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006063105-A1 | DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF | SICOR INC. (US) | 2006-06-15 | — | — | WO | disclosed |