Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.73 |
| ▸ | PGR | P06401 | 10/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202660 | 0.90 | NR3C1 (0.75) | NR3C1PGRNR3C2 | |
| SCHEMBL3647702 | 0.89 | NR3C1 (0.79) | NR3C1PGRNR3C2 | |
| SCHEMBL5202457 | 0.89 | NR3C1 (0.69) | NR3C1PGRNR3C2 | |
| SCHEMBL4824698 | 0.87 | NR3C1 (0.76) | NR3C1PGRNR3C2AR | |
| SCHEMBL3650970 | 0.87 | NR3C1 (0.76) | NR3C1PGRNR3C2ARCYP3A4 | |
| SCHEMBL4822471 | 0.85 | NR3C1 (0.81) | NR3C1PGRNR3C2ARCYP3A4 | |
| SCHEMBL4826339 | 0.85 | NR3C1 (0.84) | NR3C1PGRNR3C2AR | |
| SCHEMBL3650510 | 0.84 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3650890 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2AR | |
| SCHEMBL3651746 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |