Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896186 | 0.94 | KCNH2 (0.53) | KCNH2UBE2THPGDSHDAC2HDAC3 | |
| SCHEMBL7550033 | 0.93 | KCNH2 (0.52) | KCNH2UBE2THPGDSHDAC2HDAC3 | |
| SCHEMBL7547417 | 0.93 | KCNH2 (0.52) | KCNH2UBE2THPGDSHDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL31552815 | 0.93 | KCNH2 (0.52) | KCNH2UBE2THPGDSHDAC2HDAC3 | |
| SCHEMBL5238314 | 0.87 | UBE2T (0.48) | KCNH2UBE2THPGDSHDAC2HDAC3 | |
| SCHEMBL1989630 | 0.86 | UBE2T (0.63) | UBE2THPGDSSMOALDH1A1KDM4E | |
| SCHEMBL31352228 | 0.86 | UBE2T (0.58) | UBE2THPGDSSMOALDH1A1KDM4E | |
| SCHEMBL19836997 | 0.86 | UBE2T (0.58) | UBE2THPGDSSMOALDH1A1KDM4E | |
| SCHEMBL29784322 | 0.86 | UBE2T (0.63) | UBE2THPGDSSMOALDH1A1KDM4E | |
| SCHEMBL4850532 | 0.85 | UBE2T (0.61) | UBE2THPGDSSMOALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307444-B1 | SUBSTITUTED HETEROCYCLIC AMIDES | LILLY CO ELI (US) | 2007-10-03 | — | — | EP | claimed |