Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896186 | 0.98 | KCNH2 (0.53) | KCNH2HPGDSHDAC2HDAC3SMO | |
| Hydrochloric Acid SCHEMBL31552815 | 0.97 | KCNH2 (0.52) | KCNH2HPGDSHDAC2HDAC3SMO | |
| SCHEMBL7550033 | 0.97 | KCNH2 (0.52) | KCNH2HPGDSHDAC2HDAC3SMO | |
| SCHEMBL5202077 | 0.93 | KCNH2 (0.49) | KCNH2HPGDSHDAC2HDAC3SMO | |
| SCHEMBL4935859 | 0.84 | MAPT (0.51) | KCNH2HPGDSHDAC2HDAC3ALDH1A1 | |
| SCHEMBL29524173 | 0.84 | PARP1 (0.53) | KCNH2HPGDSHDAC2HDAC3SMO | |
| SCHEMBL2706925 | 0.84 | PARP1 (0.53) | KCNH2HPGDSHDAC2HDAC3SMO | |
| SCHEMBL31352228 | 0.83 | UBE2T (0.58) | HPGDSSMOALDH1A1OGANPC1 | |
| SCHEMBL1989630 | 0.83 | UBE2T (0.63) | HPGDSSMOALDH1A1OGANPC1 | |
| SCHEMBL29784322 | 0.83 | UBE2T (0.63) | HPGDSSMOALDH1A1OGANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885886-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN SEIFUN GROUP INC (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5972943-A | N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885886-A1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |