Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | PLD2 | O14939 | 8/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 7/20 | 0.47 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872222 | 0.91 | PLD2 (0.50) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL5871535 | 0.91 | PLD2 (0.50) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL5204133 | 0.91 | HTR2A (0.49) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL6620022 | 0.90 | PLD2 (0.46) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL5871928 | 0.90 | PLD2 (0.53) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL5871154 | 0.90 | PLD2 (0.49) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL6621516 | 0.89 | PLD2 (0.44) | HTR2AHTR2CHTR7HTR6PLD2 | |
| SCHEMBL5871452 | 0.89 | PLD2 (0.48) | HTR2AHTR2CHTR7HTR6PLD2 | |
| Oxalic Acid SCHEMBL5870981 | 0.88 | PLD2 (0.44) | HTR2AHTR2CHTR7HTR6PLD2 | |
| Oxalic Acid SCHEMBL5871790 | 0.88 | PLD2 (0.51) | PLD2PLD1CACNA1GDRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |