Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202531 | 0.79 | TSHR (0.40) | TSHRHSD17B10FAAHTRPV1KDM4E | |
| SCHEMBL5202542 | 0.79 | TSHR (0.40) | TSHRHSD17B10FAAHTRPV1KDM4E | |
| SCHEMBL9875970 | 0.76 | TSHR (0.53) | TSHRHSD17B10MGLLKCNH2 | |
| SCHEMBL9875972 | 0.76 | TSHR (0.53) | TSHRHSD17B10MGLLKCNH2 | |
| SCHEMBL5206553 | 0.76 | CNR1 (0.46) | FAAH | |
| SCHEMBL16954973 | 0.72 | CYP2A6 (0.41) | TSHRHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL5209886 | 0.72 | CYP2D6 (0.42) | CYP2D6FAAHTRPV1MGLLKCNH2 | |
| SCHEMBL5207917 | 0.72 | CYP2D6 (0.42) | CYP2D6FAAHTRPV1MGLLKCNH2 | |
| SCHEMBL5207708 | 0.72 | CYP2D6 (0.42) | CYP2D6FAAHTRPV1MGLLKCNH2 | |
| SCHEMBL5207398 | 0.72 | CYP2D6 (0.42) | CYP2D6FAAHTRPV1MGLLKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |