Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875970 | 1.00 | TSHR (0.53) | TSHRHSD17B10CYP2A6LOXL2CYP19A1 | |
| SCHEMBL9827715 | 0.78 | TSHR (0.46) | TSHRHSD17B10CYP2A6KCNH2MGLL | |
| SCHEMBL9827727 | 0.78 | TSHR (0.46) | TSHRHSD17B10CYP2A6KCNH2MGLL | |
| SCHEMBL9827722 | 0.78 | TSHR (0.46) | TSHRHSD17B10CYP2A6KCNH2MGLL | |
| SCHEMBL24916718 | 0.78 | ALDH1A1 (0.45) | TSHRHSD17B10CYP2A6MGLL | |
| SCHEMBL18364694 | 0.78 | ALDH1A1 (0.58) | TSHRHSD17B10MGLL | |
| SCHEMBL9401077 | 0.77 | TRPV1 (0.40) | KCNH2MGLL | |
| SCHEMBL20421301 | 0.77 | TOP1 (0.41) | KCNH2 | |
| SCHEMBL9401079 | 0.77 | TRPV1 (0.40) | KCNH2MGLL | |
| SCHEMBL20421302 | 0.77 | TOP1 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015473-A1 | LEUCOTRIENE ANTAGONISTS, A PREPARATION METHOD THEREFOR AND THERAPEUTIC USES THEREOF | LABORATOIRES FOURNIER S.C.A. (FR) | 1991-10-17 | — | — | WO | disclosed |