Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8843008 | 1.00 | — | — | |
| SCHEMBL11247588 | 0.98 | — | — | |
| SCHEMBL9053753 | 0.78 | PLG (0.33) | — | |
| SCHEMBL1476498 | 0.73 | — | — | |
| SCHEMBL31363274 | 0.73 | — | — | |
| Bromide SCHEMBL3154473 | 0.72 | NOTUM (0.36) | — | |
| SCHEMBL18499575 | 0.71 | — | — | |
| SCHEMBL822841 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL5356449 | 0.71 | LMNA (0.41) | — | |
| SCHEMBL6902313 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049674-B1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1049674-A1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | Aventis Pharma Deutschland GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037615-A1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-29 | — | — | WO | disclosed |