Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202792 | 0.80 | CYP2D6 (0.35) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL304967 | 0.74 | CYP2D6 (0.36) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL14224578 | 0.72 | ALDH1A1 (0.37) | — | |
| SCHEMBL614491 | 0.71 | TDP1 (0.35) | CYP3A4 | |
| SCHEMBL15183692 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL15183691 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL28066303 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL5549292 | 0.66 | CYP2D6 (0.61) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL3860451 | 0.66 | ALDH1A1 (0.32) | — | |
| SCHEMBL11159 | 0.66 | CYP2D6 (0.61) | CYP2D6SPHK1GMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868770-A1 | METHOD OF FORMING STRUCTURED ABRASIVE ARTICLE | Saint-Gobain Abrasives, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006112909-A1 | METHOD OF FORMING STRUCTURED ABRASIVE ARTICLE | SAINT-GOBAIN ABRASIVES, INC. (US) | 2006-10-26 | — | — | WO | disclosed |