Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864969 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1863529 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1872077 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1866402 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1858430 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1868781 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1860509 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1861596 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1867307 | 1.00 | GHSR (0.39) | GHSRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL1866526 | 0.98 | GHSR (0.37) | GHSRTP53CYP3A4MEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |