Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472412 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRPTGS1NFE2L2FBP1 | |
| SCHEMBL28193775 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRPTGS1NFE2L2FBP1 | |
| SCHEMBL28193732 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRPTGS1FBP1MAOA | |
| SCHEMBL6777780 | 0.80 | PTGS1 (0.61) | PTGS1NFE2L2FBP1MAOBNPC1 | |
| SCHEMBL3222249 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TSHRPTGS1FBP1MAOA | |
| SCHEMBL3222257 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TSHRPTGS1FBP1MAOA | |
| SCHEMBL10410990 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TSHRPTGS1FBP1MAOA | |
| SCHEMBL21294254 | 0.78 | ALDH1A1 (0.60) | ALDH1A1TSHRMAOAMAOBKMT2A | |
| SCHEMBL28276249 | 0.78 | ALDH1A1 (0.60) | ALDH1A1TSHRPTGS1NPC1RAB9A | |
| SCHEMBL28108410 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TSHRNFE2L2FBP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658945-A | A kind of Antitubulin（VDA-1）A crystal forms | 深圳海王医药科技研究院有限公司 | 2018-10-16 | — | — | CN | disclosed |
| US-20070265231-A1 | Hydrazide Compounds for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-15 | — | — | US | disclosed |
| CN-101068468-A | Hydrazide compounds for combating animal pests | BASF AG (DE) | 2007-11-07 | — | — | CN | disclosed |
| EP-1819224-A1 | HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058730-A1 | HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265231-A1 | Hydrazide Compounds for Combating Animal Pests | HRH4, CBR3, HRH2 | ALDH1A1 580/4885TSHR 934/4885PTGS1 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.