⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748646 | 0.70 | — | — | |
| SCHEMBL1748586 | 0.70 | — | — | |
| SCHEMBL1748644 | 0.65 | — | — | |
| SCHEMBL23929080 | 0.65 | — | — | |
| SCHEMBL4370711 | 0.61 | — | — | |
| SCHEMBL6855585 | 0.58 | — | — | |
| SCHEMBL1748588 | 0.58 | — | — | |
| SCHEMBL1600878 | 0.58 | — | — | |
| SCHEMBL8172810 | 0.57 | TSHR (0.32) | — | |
| SCHEMBL10555206 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603930-B1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-29 | — | — | EP | claimed |
| US-7141691-B2 | Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-11-28 | — | — | US | claimed |
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-04-27 | — | — | US | claimed |
| EP-1603930-B1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-29 | — | — | EP | disclosed |
| US-7141691-B2 | Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-04-27 | — | — | US | disclosed |