Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 13/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206510 | 0.92 | PIK3CD (0.59) | PIK3CDCYP11B2EPHX1CETPIKBKE | |
| SCHEMBL5203780 | 0.88 | PIK3CD (0.75) | PIK3CDLRRK2EPHX1CETPIKBKE | |
| SCHEMBL5202288 | 0.88 | PIK3CD (0.75) | PIK3CDLRRK2EPHX1CETPIKBKE | |
| SCHEMBL5200658 | 0.88 | PIK3CD (0.75) | PIK3CDLRRK2EPHX1CETPIKBKE | |
| SCHEMBL5205939 | 0.87 | PIK3CD (0.74) | PIK3CDLRRK2EPHX1CETPIKBKE | |
| SCHEMBL5206517 | 0.83 | PIK3CD (0.57) | PIK3CDCETPIKBKETBK1 | |
| SCHEMBL5205720 | 0.80 | PIK3CD (0.55) | PIK3CDCETPIKBKETBK1 | |
| SCHEMBL5201356 | 0.80 | PIK3CD (0.59) | PIK3CDLRRK2CETPIKBKETBK1 | |
| SCHEMBL5203258 | 0.80 | PIK3CD (0.55) | PIK3CDCETPIKBKETBK1 | |
| SCHEMBL5203254 | 0.80 | PIK3CD (0.60) | PIK3CDLRRK2CETPIKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682532-B1 | PYRIMIDINES AS INHIBITORS OF PHOSPHOINOSITIDE-3-KINASES (PI3K) | WARNER LAMBERT CO (US) | 2007-06-27 | — | — | EP | claimed |